cees dekker Things To Know Before You Buy
cees dekker Things To Know Before You Buy
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Human Rad51 filaments on double- and single-stranded DNA: correlating standard and irregular sorts with recombination perform.
[Laughs] ‘It absolutely was unquestionably an awesome hazard! At some time, I had been very well informed that it could go Mistaken and that I could turn out to be much less successful, but I just ignored that. Curiosity has always been my strongest driving drive. And by chance all of it worked out.’
Due to the fact 2000, Dekker has shifted the principle focus of his perform in direction of biophysics where by he reports the Attributes of single biomolecules and cells using the instruments of nanotechnology. This change of discipline was pushed by his fascination with the outstanding working of Organic molecular buildings, in addition to with the extensive-term perspective that lots of appealing discoveries can be anticipated In this particular subject.[five] Present-day lines of study in his biophysics group are inside the regions of:[six]
2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and first at any time examine from the dynamics DNA supercoils and the discovery of supercoil hopping
Our investigate ranges from the biophysics of DNA to artificial cells and further than. Please have a look below at the spectrum of our current projects.
We use nanofabricated microfluidic buildings to sample spatial boundaries for microbes and biomimetic vesicles with reconstituted protein networks which evaluate the basic position of spatial confinement with the molecular and cellular stage. Our initiatives incorporate the next:
Instance (one) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is https://www.ceesdekker.net revealed in grey, the rim of your pore is highlighted in crimson, and a 3D rendering with the motion with the DNA rod is displayed.
The rotors harness Electrical power from a nanoscale h2o and ion flow that's produced by a static chemical or electrochemical opportunity gradient during the nanopore, which can be set up through a salt gradient or used voltage, respectively. These synthetic nanoengines self-Manage and work autonomously in physiological situations, suggesting tips on how to setting up Vitality-transducing motors at nanoscale interfaces.
Bulk-area coupling identifies the mechanistic connection among Min-protein designs in vivo As well as in vitro
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Numerous new phenomena were being uncovered, and he and his study team set up a number one placement in this subject of analysis. Dekker and his research group discovered new physics of nanotubes together with explored the feasibility of molecular electronics. In 1998, they had been the main to construct a transistor dependant on an individual nanotube molecule.
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of one wire bridging two electrodes
Finally, I'll briefly sketch several of our Thoughts to discover the creating of synthetic cells, exclusively our initially techniques to determine artificial mobile division.